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San Francisco Giants jerseys starting pitcher reacts after giving up 3 runs during the fourth inning of a baseball game against the Chicago White Sox jerseys on Tuesday, June 17, 2014, in Chicago. (AP Photo/Andrew A. Cellular Field, giving up a season high eight runs on 10 hits. The Giants jerseys had been 6 0 through their first two rounds of interleague action, sweeping the Cleveland Indians jerseys and Minnesota Twins jerseys at home.

The first night in an American League park this season was a nightmare for the Giants jerseys, who have dropped seven of eight.

Cain has taken two of the losses during the run, giving up 11 earned runs over 10 innings. He didn provide specifics when asked what needed to be fixed moving forward.

biggest thing is just location, Cain said.

He missed repeatedly in the middle innings, and the slugging White Sox jerseys jumped all over him.

The blowout actually got off to a good start, with hitting a solo homer in the first and driving cheap authentic jerseys in a run in the third. But Cain couldn hold the lead for long. With two out and one on in the third, Cain grooved a 3 2 fastball to and didn even watch as the ball sailed out of the park.

The floodgates burst in the fourth, an inning that started with three of the first four White Sox jerseys reaching on singles. With the bases loaded, Cain walked catcher , who had been hitless in his previous 23 at bats with 19 strikeouts. Speedy leadoff hitter hit a slow roller to short that barehanded but threw away. Two runs came across on the infield single and error, giving the White Sox jerseys a 5 2 lead.

got off to a good start, manager Bruce Bochy said of Cain. first two innings, he looked really sharp and looked on track. He ended up giving up the homer (to Beckham) and he just got derailed. The stuff flattened out and they took advantage of Matty being wild in the zone.

happened? I can tell you, to be honest. has long referred to Cain as his he did again after Tuesday game and he sent Cain out for the fifth. After two singles and a wild pitch added up to a sixth run, Cain hung a changeup to Dayan Viciedo that was supposed to be down in the dirt. The right fielder hit a no doubter high up the left field seats.

Cain said he felt fine on the mound, but admitted at times he didn get the ball down in the zone enough, or in on hitters hands.

felt confident in everything I was throwing, he said. was a really bad changeup to Viciedo. The other ones weren terrible but they caught too much plate, and they going to take advantage of it. dropped to 1 5 and his ERA ticked up to 4.52. The starters have a 5.25 ERA during the eight game stretch, but Tim Hudson, the best of the bunch this season, takes the ball Wednesday in the second game of a short two game series. Even with Hudson on the mound, the Giants jerseys still face an uphill battle. They face (1.97 ERA, 0.67 WHIP), a hard throwing All Star who might be the best left hander in the game.

Bochy was in the opposing dugout when Sale pitched for the American League All Star team last year. What memory stood out to Bochy?

had one hitter say, hope I don have to face Sale, he said Tuesday.

Leadoff hitter Angel Pagan was out of the lineup for a second straight game because of back inflammation. Bochy said an MRI revealed no structural damage and there has been no talk of putting Pagan on the disabled list.

trying to get this under control, Bochy said. was making a little progress, but not as much as we would hope. has been out of the starting lineup 14 times this season, most often because of a sore right knee.